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Cytokine expression in the lungs of mice infected with H9N2/Y280 and the D253N mutant in PB2. The lungs of virus-infected mice were collected from days 3 and 6 postinoculation, and A IP-10, B MCP-3, C MCP-1, D MIP-1α, E MIP-1β, and F TNF-α levels were measured by bead ELISAs. Results from each time point are expressed as means ± standard deviations of three infected mice (n = 3).
