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Table 2.

Stage Distribution of LDCT Screen-Detected Cancers According to Nodule Size on Screen

Average Nodule Sizea NSCLC
SCLC
No. % Stage I % Stage III/IV No. % Stage I % Stage III/IV
3 to < 7 mm 40 73 15 7 14 86
7 to < 10 mm 83 81 14 1 0 100
10 to < 15 mm 122 79 16 4 0 75
15 to < 20 mm 79 75 14 5 0 80
20 to < 30 mm 55 69 24 3 0 67
≥ 30 mm 32 34 59 3 0 100
Allb 587 67 25 46 4 85

Three unknown-stage small cell lung cancer (SCLC) cases were excluded, including one case with one noncalcified nodule (NCN) in the cancer lobe (size, 10-14 mm). Nine unknown-stage non-small cell lung cancer (NSCLC) cases were excluded, including seven cases with one NCN in the cancer lobe (two 7-9 mm, two 10-14 mm, two 15-19 mm, and one 20-29 mm). Also excluded were three NSCLC cases with one NCN in the cancer lobe but unknown size of the NCN. See Table 1 legend for expansion of other abbreviation.

a

Average of longest diameter and longest perpendicular. Analysis limited to subjects with one (and only one) NCN in the lobe of the cancer at screen detection.

b

Includes subjects with 0 or ≥ 2 NCNs in the cancer lobe, and with unknown lobe of the cancer.