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FCs vaccination attenuates advanced lesion. (A) Experimental design of the therapeutic study. (B) En face lesion size of the whole aorta. (C) Plaque size in the three-valve area of the aortic root. (D) Collagen content in the aortic root. Scale bars, 200 μm. All data are presented as mean ± SEM and are representative of all mice. n = 5–6 in each group; *p < 0.05; **p < 0.01; ***p < 0.001.
