Table 1.
Demographics and neuropsychological testing.
| aMCI-c (n = 26) | aMCI-nc (n = 26) | HC (n = 26) | F value | P-value | |
|---|---|---|---|---|---|
| Age (years) | 67.7 ± 8.1 (50–78) | 67.7 ± 8.3 (50–78) | 67.8 ± 8.0 (50–78) | 0.01 | 0.99* |
| Gender(M/F) | 12/14 | 14/12 | 13/13 | – | 0.86# |
| Education (years) | 10.1 ± 5.0 (0–20) | 9.4 ± 5.0 (0–18) | 11.2 ± 5.4 (0–18) | 0.63 | 0.54* |
| MMSE | 23.1 ± 2.9 (17–28) | 25.3 ± 3.5 (18–30) | 28.0 ± 2.3 (20–30) | 20.29 | <0.001*abc |
| MoCA | 17.6 ± 3.1 (10–23) | 20.6 ± 4.0 (14–26) | 26.5 ± 1.5 (25–30) | 58.54 | <0.001*abc |
| AVLT-Immediate Recall | 4.8 ± 1.2 (2.7–7.3) | 5.8 ± 1.7 (3.3–10.0) | 9.3 ± 2.0 (2.7–14.7) | 53.07 | <0.001*bc |
| AVLT-Delayed Recall | 2.7 ± 2.1 (0–6) | 3.5 ± 3.1 (0–11) | 10.1 ± 2.8 (4–15) | 59.08 | <0.001*bc |
| AVLT-Recognition | 6.5 ± 3.9 (−3–13) | 7.5 ± 3.7 (0–14) | 12.2 ± 2.3 (5–15) | 20.22 | <0.001*bc |
Values are represented as the mean ± SD (range). All of the scores are raw values.
HC, healthy control; aMCI, amnestic mild cognitive impairment; aMCI-c, aMCI converters; aMCI-nc, aMCI non-converters; MMSE, Mini-Mental State Examination (Chinese Version); MoCA, Montreal Cognitive Assessment (Beijing Version); AVLT, Auditory Verbal Learning Test.
The P-values were obtained using one-way analysis of variance (ANOVA). Post-hoc pairwise comparisons were performed using a t-test. P < 0.05 was considered significant.
The P-values were obtained using the Kruskal-Wallis one-way ANOVA.
post-hoc paired comparisons showed a significant group difference between aMCI-c vs. aMCI-nc.
post-hoc paired comparisons showed a significant group difference between aMCI-c vs. HC.
post-hoc paired comparisons showed a significant group difference between aMCI-nc vs. HC.