Table 2.
Reports of IVIG treatment in EBA.
| Reported year | Reference | Age | Sex | Phenotype of EBA | Treatments prior to IVIG | Regimen of IVIG | Concomitant-started treatment | Outcome |
|---|---|---|---|---|---|---|---|---|
| 2013 | (115) | 37 | f | BP-like | Corticosteroid, colchicine, DDS | 2 g/kg/cycle | No response | |
| 2013 | (116) | 20 | f | BP-like | Corticosteroid, DDS | 500 mg/kg/day, 4 days | colchicine (1 mg/day) | CR |
| 2013 | (117) | 2 | m | BP-like | Corticosteroid | 400 mg/kg/day, 4 days | DDS (1 mg/kg/day) | PR |
| 2011 | (118) | 55 | f | BP-like | Corticosteroid, AZA | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 61 | m | Mechanobullous | Corticosteroid, DDS | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 37 | m | Mechanobullous | Corticosteroid, DDS | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 55 | f | Mechanobullous | Corticosteroid, DDS | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 47 | f | Mechanobullous | Corticosteroid | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 50 | f | Mechanobullous | DDS, MMF, MTX | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 73 | m | Mechanobullous | Corticosteroid, DDS | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 75 | f | Mechanobullous | Corticosteroid, DDS | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 59 | m | BP-like | Colchicine, CSA | 2 g/kg/cycle divided in 3 days | CR | |
| 2011 | (118) | 62 | f | BP-like | Colchicine, MTX, MFM | 2 g/kg/cycle divided in 3 days | CR | |
| 2007 | (119) | 70 | m | Unknown | Corticosteroid, AZA, DDS, CSA | 2 g/kg/cycles | PR | |
| 2007 | (120) | 65 | m | Mechanobullous (+p200 pemphigoid) | Corticosteroid, DDS, CSA, MMF | 400 mg/kg/day, 5 days | PR | |
| 2007 | (121) | 58 | f | Unknown | Corticosteroid, AZA, MMF, CSA | 2 g/kg/cycles | no response | |
| 2006 | (63) | 22 | m | Unknown | Corticosteroid, DDS | 2 g/kg/cycle divided in 3 days | PR (4 cycles later) | |
| 2006 | (122) | 54 | f | Mechanobullous | Corticosteroid, AZA, colchicine, | 2 g/kg/cycle divided in 5 days | PR (4 cycles later) | |
| 2002 | (123) | 43 | f | Both | None | 400 mg/kg/day, 5 days | CR (PR after 1 cycle) | |
| 2000 | (124) | 37 | m | BP-like | Corticosteroid | 1.2 g/kg/cycle divided in 2–3 days | CR (after 9 months) | |
| 1998 | (46) | 59 | m | Mechanobullous | Corticosteroid, DDS, MTX, CSA, CPA, IA | 400 mg/kg/day, 5 days | CR | |
| 1997 | (125) | 29 | m | BP-like | Corticosteroid, AZA, DDS, PE, colchicine, CSA | 40 mg/kg/day, 5 days | CR (after 4 cycles) | |
| 1995 | (126) | 55 | m | BP-like | Corticosteroid, AZA, DDS, colchicine | 400 mg/kg/day, 5 days | CR (after 9 cycles) | |
| 1993 | (127) | 16 | m | Both | Corticosteroid, CSA | 400 mg/kg/day, 4 days every 2 weeks | CR |
BP, bullous pemphigoid; DDS, diaminodiphenyl sulfone; MTX, methotrexate; AZA, azathioprine; CSA, cyclosporine; MMF, mycophenolate mofetil; CPA, cyclophosphamide; IVIG, high-dose intravenous immunoglobulin; PE, plasma exchange; CR, complete remission; PR, partial remission.