Table 1.

The most investigated predictive factors influencing CR response in schizophrenia.

Patient predictive factors

Age

DOI

Phase of illness

Chronicity (number of hospitalizations)

Diagnosis

Premorbid functioning (adjustment)

Pretreatment symptoms severity (positive, negative, disorganized symptoms and hostility)

Pretreatment cognition

Pretreatment functioning

Psychological characteristics (depressed mood, anxiety, cooperative attitude, intrinsic motivation)

Cognitive change after CR and functional outcome

Neurobiological predictive factors (cognitive reserve, genetic variability)

Treatment predictive factors

Presence of the therapist

The role of the therapist

Therapeutic alliance

CR characteristics (type of CR treatment)

CACR

Use of strategic CR

Use of drill and practice CR

Use of massed practice

Pharmacological treatment (amounts of antipsychotics intake)

Presence of integrated treatment

CACR, Computer-Assisted Cognitive Remediation; CR, Cognitive Remediation; DOI, Duration of Illness.