Table 2.

Predictive factors influencing CR response in schizophrenia: literature main findings.

Patient positive response predictors	Treatment positive response predictors
Younger age	Presence of a highly trained therapist
Shorter DOI	The active role of the therapist
Early phase of illness	Therapeutic alliance
Lower pretreatment disorganized symptoms	Use of strategic CR
Lower pretreatment hostility	Use of massed practice
Lower pretreatment negative symptoms	Presence of integrated treatment
Greater intrinsic motivation	Lower amounts of antipsychotics intake at baseline
Greater cognitive improvement after CR	Lower anticholinergic burden at baseline
Greater pretreatment cognitive reserve
Patient controversial predictors	Treatment controversial predictors
Chronicity (number of hospitalizations)	Type of CR treatment (CACR vs. non-CACR)
Diagnosis	Use of drill and practice CR
Premorbid functioning (adjustment)
Cognitive impairment at baseline
Functional impairment at baseline
Genetic variability

CACR, Computer-Assisted Cognitive Remediation; CR, Cognitive Remediation; DOI, Duration of Illness.