Table 2.

Characteristics of included studies on vitamin D receptor gene polymorphisms and polycystic ovary syndrome risk.

References	Country/region	Racial	Source of controls	Case	Control	Genotype distribution						Genotyping methods	P for HWE	MAF in control	NOS
						Case			Control
						Fok I C/T (rs10735810)
						CC	CT	TT	CC	CT	TT
Mahmoudi, 2009	Iran	Caucasian	Hospital-B	162	162	83	67	12	96	59	7	PCR-RFLP	0.58	0.23	8
Wehr et al., 2011	Austria	Caucasian	Hospital-B	538	135	215	241	82	53	60	22	Genotyping assay	0.47	0.39	8
Bagheri et al., 2012	Iran	Caucasian	Healthy-B	46	46	22	20	4	29	15	2	PCR-RFLP	0.97	0.21	7
Jedrzejuk et al., 2015	Poland	Caucasian	Healthy-B	90	98	28	51	11	23	50	25	PCR- SNaPshot	0.84	0.51	7
Dasgupta et al., 2015	India	Asian	Healthy-B	250	250	155	85	10	153	82	15	PCR-RFLP	0.37	0.22	8
Mahmoudi et al., 2015	Iran	Caucasian	Healthy-B	35	35	16	17	2	24	10	1	PCR-RFLP	0.97	0.17	8
Cao and Tu, 2016	China	Asian	Hospital-B	120	120	70	40	10	65	45	10	PCR-RFLP	0.60	0.27	7
						BsmI A/G (rs1544410)
						AA	AG	GG	AA	AG	GG
Mahmoudi, 2009	Iran	Caucasian	Hospital-B	162	162	24	85	53	18	91	53	PCR-RFLP	0.02	0.61	8
Wehr et al., 2011	Austria	Caucasian	Hospital-B	537	137	77	244	216	22	66	49	Genotyping assay	0.98	0.60	8
Bagheri et al., 2012	Iran	Caucasian	Healthy-B	46	46	15	27	4	20	24	2	PCR-RFLP	0.12	0.30	7
Jedrzejuk et al., 2015	Poland	Caucasian	Healthy-B	90	98	14	45	31	13	42	43	PCR- SNaPshot	0.59	0.65	7
Mahmoudi et al., 2015	Iran	Caucasian	Healthy-B	35	35	10	12	13	5	23	7	PCR-RFLP	0.06	0.53	8
Cao and Tu, 2016	China	Asian	Hospital-B	120	120	23	60	37	40	55	25	PCR-RFLP	0.45	0.44	7
Siddamalla et al., 2018	India	Asian	Hospital-B	95	130	35	45	15	72	41	17	PCR-RFLP	0.01	0.29	7
						ApaI A/C (rs7975232)
						AA	AC	CC	AA	AC	CC
Mahmoudi, 2009	Iran	Caucasian	Hospital-B	162	162	58	68	36	49	90	23	PCR-RFLP	0.07	0.42	8
Wehr et al., 2011	Austria	Caucasian	Hospital-B	543	145	142	274	127	48	60	37	Genotyping assay	0.04	0.46	7
El-Shal et al., 2013	Egypt	Caucasian	Healthy-B	150	150	63	65	22	68	64	18	PCR-RFLP	0.62	0.33	8
Jedrzejuk et al., 2015	Poland	Caucasian	Healthy-B	90	98	19	52	19	32	49	17	PCR- SNaPshot	0.81	0.42	7
Dasgupta et al., 2015	India	Asian	Healthy-B	250	250	117	120	13	122	116	12	PCR-RFLP	0.02	0.28	7
Mahmoudi et al., 2015	Iran	Caucasian	Healthy-B	35	35	15	11	9	8	21	6	PCR-RFLP	0.23	0.47	8
Cao and Tu, 2016	China	Asian	Hospital-B	120	120	22	58	40	39	55	26	PCR-RFLP	0.43	0.45	7
Siddamalla et al., 2018	India	Asian	Hospital-B	95	130	42	21	32	70	35	25	PCR-RFLP	< 0.01	0.33	7
						TaqI T/C (rs731236)
						TT	TC	CC	TT	TC	CC
Mahmoudi, 2009	Iran	Caucasian	Hospital-B	162	162	71	71	20	72	76	14	PCR-RFLP	0.33	0.32	8
Wehr et al., 2011	Austria	Caucasian	Hospital-B	536	137	226	238	72	49	65	23	Genotyping assay	0.85	0.41	8
Bagheri et al., 2013	Iran	Caucasian	Healthy-B	38	38	16	14	8	17	19	2	PCR-RFLP	0.26	0.30	7
El-Shal et al., 2013	Egypt	Caucasian	Healthy-B	150	150	40	74	36	69	61	20	PCR-RFLP	0.27	0.34	8
Jedrzejuk et al., 2015	Poland	Caucasian	Healthy-B	90	98	37	45	8	49	37	12	PCR- SNaPshot	0.24	0.31	7
Dasgupta et al., 2015	India	Asian	Healthy-B	250	250	112	91	47	109	104	37	PCR-RFLP	0.14	0.36	8
Mahmoudi et al., 2015	Iran	Caucasian	Healthy-B	35	35	15	14	6	15	16	4	PCR-RFLP	0.93	0.34	8
Cao and Tu, 2016	China	Asian	Hospital-B	120	120	57	52	11	40	72	8	PCR-RFLP	< 0.01	0.37	6
Siddamalla et al., 2018	India	Asian	Hospital-B	95	130	40	31	24	71	42	17	PCR-RFLP	0.01	0.29	7

HWE in control. MAF, Minor allele frequency in control group; Hospital-B, Hospital-based control; Healthy-B, Healthy-based control.