Table 4.
Sensitivity and specificity of the SediVue (SW1.0.1.3) in comparison to manual microscopy for the detection of formed elements in canine (n = 432) versus feline (n = 98) urine using thresholds of ≥5/hpf for RBC and WBC and ≥1/hpf for sqEPI, nsEPI, STR, and CaOx Di
| Sensitivity (95% CI) | Specificity (95% CI) | |||
|---|---|---|---|---|
| Canine | Feline | Canine | Feline | |
| RBC | 87.6% (80.4%‐92.9%) | 92.0% (80.8%‐97.8%) | 91.0% (87.3%‐93.9%) | 85.4% (72.2%‐93.9%) |
| WBC | 88.6% (81.3%‐93.8%) | 58.3% (27.7%‐84.8%) | 87.7% (83.6%‐91.1%) | 91.9% (84.0%‐96.7%) |
| sqEPI | 30.4% (13.2%‐52.9%) | N/A (2.5%‐100.0%) | 99.3% (97.9%‐99.9%) | 100.0% (96.3%‐100.0%) |
| nsEPI | 71.4% (56.7%‐83.4%) | N/A (29.0%‐96.3%) | 85.4%a (81.4%‐88.8%) | 95.6%a (89.1%‐98.8%) |
| STR | 90.2% (82.7%‐95.2%) | 92.0% (74.0%‐99.0%) | 83.3% (78.9%‐87.2%) | 89.0% (79.5%‐95.2%) |
| CaOx Di | 79.6% (65.7%‐89.8%) | N/A (0.0%‐70.8%) | 99.5% (98.1%‐99.9%) | 97.9% (92.6%‐99.7%) |
Abbreviations: CaOx Di, calcium oxalate dihydrate crystals; CI, confidence intervals; hpf, high power field; nsEPI, non‐squamous epithelial cells; N/A, not applicable because of wide confidence interval; RBC, red blood cells; sqEPI, squamous epithelial cells; STR, struvite crystals; WBC, white blood cells.
a
Comparisons in which confidence intervals did not overlap.