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. 2018 Dec 5;33(1):212–224. doi: 10.1111/jvim.15358

Table 5.

ROC curve statistics for RMSSD to predict the presence of arrhythmia (including only horses with arrhythmias occurring in each separate phase)

Phase AUC (95% CI) P‐value RMSSD cutoff Sn (%) (95% CI) Sp (%) (95% CI) LR
Trot 0.82 (0.55‐1.1) P = .01 High Sn 3.7 100 (54%‐100%) 10 (3.5%‐23%) 1.1
Youden index 6.7 83 (36%‐100%) 83 (70%‐93%) 5
High Sp 8.8 67 (22%‐96%) 98 (89%‐100%) 32
Canter 0.72 (0.54‐0.91) P = .04 High Sn 4.6 100 (63%‐100%) 33 (20%‐48%) 1.5
Youden index 6.7 63 (24%‐91%) 72 (57%‐84%) 2.2
High Sp 12 25 (3.2%‐65%) 98 (88%‐100%) 12
Recovery 0.98 (0.95‐1) P < .0001 High Sn 5.2 100 (86%‐100%) 67 (47%‐83%) 3
Youden index 6.4 96 (79%‐100%) 93 (78%‐99%) 14
High Sp 7.3 83 (63%‐95%) 97 (83%‐100%) 25

Abbreviations: AUC, area under curve; LR, likelihood ratio; RMSSD, square root of mean‐squared differences in successive R‐R intervals; ROC curve, receiver operating characteristic curve; Sn, sensitivity; Sp, Specificity.