Table 1.
Dog characteristics
| NL (n = 7) | CH (n = 8) | LC (n = 7) | P‐value | |
|---|---|---|---|---|
| Sex | 1M, 3MC, 3FS | 1F, 7FS | 6MC, 1FS | |
| Age (y) | 4.8 (1.6‐8.1) | 8.7 (5.2‐11.4)* | 9.2 (6.1‐12.1)* | .01 |
| ALT (U/L) | 44 (27‐56) | 416 (68‐779)** | 508 (78‐712)** | <.001 |
| BA (μmol/L) | 1 (1‐2) | 12 (1‐95) | 72 (40‐161)*** | <.001 |
| Grade of hepatitis | 0 (0‐0) | 2 (0‐3)* | 2 (1‐3)** | .001 |
| Stage of fibrosis | 0 (0‐0) | 2 (1‐3) | 4 (3‐4)*** | <.001 |
| Copper scoring | 0 (0‐1) | 2 (1‐2.5)* | 2 (0‐4)* | <.001 |
Data are expressed as median (range).
Abbreviations: ALT, alanine aminotransferase; BA, bile acids; CH, chronic hepatitis; F, female; FS, female spayed; LC, liver cirrhosis; NL, normal liver; M, male; MC, male castrated.
*
P < .05 compared with NL.
**
P < .01 compared with NL.
***
P < .001 compared with NL.