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. 2019 Jan 10;9:1937. doi: 10.3389/fphys.2018.01937

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Copyright © 2019 Chakrabarty, Bijos, Vahabi, Clavica, Kanai, Pickering, Fry and Drake.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Representative trace of the effect of 18β-GA (30 μM) on CCh-induced contractions in denuded strips, including an insert of the control, drug, and washout. The effects of 18β-GA (10 and 30 μM) and CBX (50 μM) in denuded strips on the (B) amplitude and (C) frequency of CCh-induced contractions. The effects of 18β-GA (10 and 30 μM) in intact strips on the (D) amplitude and (E) frequency of spontaneous and CCh-induced contractions. The effects of CBX (50 μM) in intact strips on the (F) amplitude and (G) frequency of spontaneous and CCh-induced contractions. ^∗P < 0.05, ^∗∗∗P < 0.001; Student’s paired t-test.