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. 2019 Jan 7;91(2):1659–1664. doi: 10.1021/acs.analchem.8b05387

Figure 1.

Figure 1

Products from CAD of (a) (M – 3H)3–, (b) (M + VR – 3H)3–, (c) (M + RR – 3H)3–, and (d) (M + Tma – 4H)3– ions of RNA 1 versus laboratory-frame collision energy illustrate the competition between covalent RNA backbone bond cleavage into c/y, a/w, or i fragments (blue) and noncovalent bond dissociation into free RNA (red) and ligand; energies required for 50% complex dissociation and 50% fragment formation are indicated by arrows.