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(a) Collision energy required for 50% complex dissociation by cleavage of noncovalent bonds (E50(nc), ▽) and for 50% fragment formation by cleavage of covalent RNA backbone bonds (E50(c), △) in CAD of complexes with RNA 1 and net charge of −3, and (b) E50(nc) in % of E50(c), versus the number of HB donor atoms of the ligands; lines are linear fit functions and the gray area in (b) illustrates the 99% confidence interval.
