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. Author manuscript; available in PMC: 2019 Jan 17.
Published in final edited form as: Adv Exp Med Biol. 2015;815:217–238. doi: 10.1007/978-3-319-09614-8_13

Table 1.

Metabolic signature of chronic alcohol exposure in the wild-type mice

 Identity  Putative origin  Trend in B6  Trend in 129S
 Ethyl sulfate  Alcohol metabolism  −  ↑
 Ethyl-β-d-glucuronide  Alcohol metabolism  ↑  ↑
 N-Acetylglycine  Alcohol metabolism  ↑  ↑
 4-Hydroxyphenylacetic acid  Phenylalanine metabolism and gut flora  −  ↑
 4-Hydroxyphenylacetic acid sulfate  Phenylalanine metabolism and gut flora  −  ↑
 2-Hydroxyphenylacetic acid  Phenylalanine metabolism and gut flora  −  ↓
 Xanthurenic acid  Tryptophan metabolism and gut flora  ↑  −
 Adipic acid  Fatty acid ω-oxidation  −  ↓
 Pimelic acid  Fatty acid ω-oxidation  −  ↓
 Taurine  Cysteine metabolism  ↓  ↑
 N-hexanoylglycine  Fatty acid β-oxidation and gut flora  ↑  −