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. 2019 Jan 17;16:5. doi: 10.1186/s12989-018-0288-7

Table 4.

Quantification of dopaminergic and cholinergic inputs in GD28 olfactory tubercles

Control Exposed Effects of DE exposure Effects of Sex Exposure × Sex
Male (n = 4) Female (n = 4) Male (n = 8) Female (n = 5) F (1,16) p-value F (1,16) p-value F (1,16) p-value
TH-labeling density (DO/surface unit, a.u) 21.27 ± 4.65 17.86 ± 4.84 15.89 ± 2.34 12.14 ± 4.11 2.461 0.143 1.080 0.319 0.001 0.980
AChe activity (μmol/min/g) 12.25 ± 0.34 9.21 ± 0.83 10.96 ± 0.85 10.66 ± 0.85 0.006 0.942 8.462 0.013* 5.773 0.033*

Relative mean density of TH+ labeled fibers in the olfactory tubercle. The quantitative estimation did not show any significant difference between the two groups

Relative mean density of AChE activity in the olfactory tubercle. There is no significant difference between the two groups regarding the DE exposure. However, we observed a sex-dependent difference between the two groups, which interacted significantly with DEP exposure. *p < 0.05