Table 2.
Univariate Analysis of positive pulmonary and mediastinal lymph nodes (pN1+, pN2+)
| Variables | pN1- (%) | pN1+ (%) | P-Value | pN2- (%) | pN2+ (%) | P-Value |
|---|---|---|---|---|---|---|
| Sex | 0.148 | 0.627 | ||||
| male | 90 (63.4) | 52 (36.6) | 112 (78.9) | 30 (21.1) | ||
| female | 46 (74.2) | 16 (25.8) | 47 (75.8) | 15 (24.2) | ||
| Age | 0.298 | 0.237 | ||||
| ≤ 68 years | 68 (63) | 40 (37) | 88 (81.5) | 20 (81.5) | ||
| > 68 years | 68 (70.8) | 28 (29.2) | 71 (74.0) | 25 (21.2) | ||
| Tumor site | 0.067 | 0.783 | ||||
| right | 90 (71.4) | 36 (28.6) | 99 (78.6) | 27 (21.4) | ||
| left | 46 (59) | 32 (41) | 60 (76.9) | 18 (23.1) | ||
| Tumor localization | < 0.001 | 0.02 | ||||
| central | 25 (47.2) | 28 (52.8) | 36 (66.7) | 18 (33.3) | ||
| peripheral | 111 (74.5) | 38 (25.5) | 122 (81.9) | 27 (18.1) | ||
| Tumor size | 0.011 | 0.042 | ||||
| ≤ 3 cm | 77 (75.5) | 25 (24.5) | 86 (84.3) | 16 (15.7) | ||
| > 3 cm | 59 (57.8) | 43 (42.8) | 73 (71.6) | 29 (28.4) | ||
| Lobe distribution | 0.918 | 0.385 | ||||
| ULa | 85 (66.4) | 43 (33.6) | 97 (75.8) | 31 (24.2) | ||
| Non-UL | 51 (67.1) | 25 (32.9) | 62 (81.6) | 14 (18.4) | ||
| pT-category | 0.015 | 0.081 | ||||
| pT1 | 70 (77.8) | 20 (22.2) | 77 (85.6) | 13 (14.4) | ||
| pT2 | 33 (61.1) | 21 (38.9) | 40 (74.1) | 14 (25.9) | ||
| pT3 | 18 (51.4) | 17 (48.6) | 23 (65.7) | 12 (34.3) | ||
| pT4 | 13 (56.5) | 10 (43.5) | 17 (73.9) | 6 (26.1) | ||
| pR-classification | 0.017 | 0.088 | ||||
| R0 | 130 (68.8) | 59 (31.2) | 150 (79.4) | 39 (20.6) | ||
| R1–2 | 5 (35.7) | 9 (64.3) | 8 (57.1) | 6 (42.9) | ||
| pL-status | < 0.001 | < 0.001 | ||||
| pL0 | 55 (96.5) | 2 (3.5) | 56 (98.2) | 1 (1.8) | ||
| pL1 | 80 (54.8) | 66 (45.2) | 102 (69.9) | 44 (30.1) | ||
| pV-status | 0.006 | 0.004 | ||||
| pV0 | 117 (70.9) | 48 (29.1) | 135 (81.1) | 30 (18.2) | ||
| pV | 18 (47.4) | 20 (52.6) | 23 (60.5) | 15 (39.5) | ||
| Pn-Status | 0.088 | 0.34 | ||||
| Pn0 | 131 (67.9) | 62 (32.1) | 149 (77.2) | 44 (22.8) | ||
| Pn1 | 4 (40.0) | 6 (60.0) | 9 (90.0) | 1 (10.0) | ||
| Histological tumor type | 0.214 | 0.646 | ||||
| Adeno-Ca.b | 84 (71.8) | 33 (28.2) | 94 (80.3) | 23 (19.7) | ||
| 56 (74.4) | 19 (25.6) | |||||
| SCCc | 45 (60.0) | 30 (40.0) | 9 (75.0) | 3 (25.0) | ||
| others | 7 (58.3) | 5 (41.7) | ||||
| Grading | 0.016 | 0.001 | ||||
| G1 | 25 (89.3) | 3 (10.7) | 27 (96.4) | 1 (3.6) | ||
| G2 | 64 (67.4) | 31 (32.6) | 79 (83.2) | 16 (16.8) | ||
| G3 | 39 (57.4) | 29 (42.6) | 43 (63.2) | 25 (36.8) | ||
| G4 | 7 (58.3) | 5 (41.7) | 9 (75.0) | 3 (25.0) | ||
aUL Upper lobe,b Adeno-Ca. Adenocarcinoma , cSCC Squamous cell carcinoma