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. 2019 Jan 16;11:8. doi: 10.1186/s13148-018-0605-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Upregulating H3K27me3 levels sensitizes OS to cisplatin in vivo. a Macroscopic image of tumor size after mice were sacrificed. Tumor volume (b) and weight (c) were measured at the indicated times. d H&E, TUNEL, cleaved Caspase 3, Ki67, and CD31 staining of representative tumors harvested from mice. **P < 0.01. Asterisk marks cell debris