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. 2019 Jan 16;11:8. doi: 10.1186/s13148-018-0605-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Alterations in H3K27me3 regulate apoptosis- and stemness-related genes involved in OS chemosensitivity to cisplatin. a Heatmap of differential gene expression profiles based on RNAseq. b Functional protein association network analysis of differential gene expression profiles based on RNAseq. c Venn diagram showing the number of differentially expressed genes in and shared between the indicated groups. d RT-qPCR analysis of PRKCA, BMF, BAX, MCL1, BCL2, MYC, KLF4, SOX9, and CD117 expression. ^#P < 0.05, ^##P < 0.01 compared with the Ctrl group.*P < 0.05, **P < 0.01 compared with the Cis group