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. 2019 Jan 16;20:31. doi: 10.1186/s12859-018-2588-1

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© The Author(s). 2019

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Screenshot of the MITK workbench and the curve description parameters plug-in that enables calculation of several semi-quantitative parameters, like the area-under-the-curve (AUC), time-to-peak and maximum signal. The images show the AUC calculated from the 4D DCE MRI data of a glioblastoma patient