Table 3.
Top 20 genes undergoing positive selection in D. aldrichi. Orthogroups with Bonferroni corrected p-value < 1.0e− 20 and Likelihood ratio test statistic estimate from aBSREL > 82. Functional information for each gene was summarised based on Flybase descriptions for D. melanogaster orthologues, classification of the protein sequence using gene ontology and/or Pfam family annotations. Asterisks indicate two genes which also have inparalogues in the D. aldrichi branch
| D. aldrichi gene | D. melanogaster orthologue | Gene name | Gene function |
|---|---|---|---|
| DALD015788* | FBgn0001341 | lethal (1) 1Bi (l(1)1Bi) | Transcriptional regulator during larval and embryo stages |
| DALD015521 | FBgn0034583 | CG10527 | DUF3421; Farnesoic acid O-methyl transferase |
| DALD011516 | FBgn0034031 | CG12963 | NA |
| DALD011555 | FBgn0029518 | CG13376 | NA |
| DALD014639 | FBgn0038654 | CG14298 | Serine-type endopeptidase inhibitor activity |
| DALD008141 | FBgn0037244 | CG14647 | Transcriptional regulator of protein homo-oligomerisation |
| DALD001586 | FBgn0029686 | CG2941 | NA |
| DALD015580* | FBgn0050440 | CG30440 | Involved in positive regulation of Rho protein signal transduction |
| DALD010188 | FBgn0266566 | CG45105 | Centrosome organising gene |
| DALD004399 | FBgn0038921 | CG6332 | Testicular haploid expressed repeat |
| DALD000608 | FBgn0036179 | CG7368 | Transcription factor regulating phagocytosis |
| DALD007329 | FBgn0045495 | Gustatory receptor 28b (Gr28b) | Taste receptor involved in perception of chemical stimuli |
| DALD007082 | FBgn0032416 | Gustatory receptor 33a (Gr33a) | Taste receptor involved in perception of chemical stimuli and courtship behaviour |
| DALD009511 | FBgn0031275 | metabotropic GABA-B receptor subtype 3 (GABA-B-R3) | G-protein coupled receptor regulating glucose metabolic processes |
| DALD010061 | FBgn0051025 | Protein phosphatase 1c interacting protein 1 (Ppi1) | DUF4788, involved in protein phosphatase binding |
| DALD012340 | FBgn0003460 | sine oculis (so) | Homeobox gene regulating circadian rhythm, reproduction and development |
| DALD002312 | FBgn0260861 | TRAPP subunit 23 (Trs23) | Trafficking protein involved in vesicle-mediated transport |
| DALD007827 | FBgn0033055 | Tubulin-specific chaperone E (Tbce) | Regulates neurogenesis and neuromuscular synaptic transmission |
| DALD005587 | FBgn0085362 | Vitellin membrane-like (Vml) | vitellin membrane formation and dorsal/ventral axis specification |
| DALD009987 | FBgn0015569 | α-Esterase10 (α-Est10) | Regulator of imaginal disc-derived wing morphogenesis |