Table 2.
Demographic and clinical characteristics of acute ischemic stroke patients with incidence of dyslipidemia stratified by rtPA and gender status.
| Received rtPA | Excluded from rtPA | |||||
|---|---|---|---|---|---|---|
| Male | Female | p-value | Male | Female | p-value | |
| Number of Patients | 182 | 143 | 203 | 241 | ||
| Age Group: No. (%) | ||||||
| <50 years | 13 (7.1) | 15 (10.5) | 0.002* | 14 (6.9) | 11 (4.6) | 0.001* |
| 50-59 | 46 (25.3) | 16 (11.2) | 23 (11.3) | 29 (12.0) | ||
| 60-69 | 45 (24.7) | 35 (24.5) | 62 (30.5) | 37 (15.4) | ||
| 70-79 | 45 (24.7) | 30 (21.0) | 54 (12.6) | 75 (31.1) | ||
| >80 years | 33 (18.1) | 47 (32.9) | 50 (24.6) | 89 (36.9) | ||
| Mean ± SD | 66.5±11.7 | 70.4±14.9 | 0.011* | 69.9±12.7 | 73.6±12.7 | 0.002* |
| Race: No. (%) | ||||||
| Caucasian | 151 (83.0) | 115 (80.4) | 0.835 | 167 (82.3) | 194 (80.5) | 0.667 |
| African-American | 29 (15.9) | 26 (18.2) | 32 (15.8) | 44 (18.3) | ||
| Other | 2 (1.1) | 2 (1.4) | 4 (2.0) | 3 (1.2) | ||
| Medical History: No. (%) | ||||||
| Hypertension | 167 (91.8) | 131 (91.6) | 0.961 | 176 (86.7) | 214 (88.8) | 0.501 |
| Coronary Artery Disease | 84 (46.2) | 40 (28.0) | 0.001* | 96 (47.3) | 87 (36.1) | 0.017* |
| Dyslipidemia | 74 (53.2) | 63 (54.3) | 0.864 | 41 (51.9) | 26 (45.6) | 0.469 |
| Atrial Fib/Flutter | 29 (15.9) | 27 (18.9) | 0.485 | 53 (26.1) | 71 (29.5) | 0.433 |
| Previous Stroke | 54 (29.7) | 36 (25.2) | 0.369 | 76 (37.4) | 90 (37.3) | 0.984 |
| Previous TIA | 31 (17.0) | 15 (10.5) | 0.093 | 31 (15.3) | 26 (10.8) | 0.160 |
| Congestive Heart Failure | 18 (9.9) | 15 (10.5) | 0.859 | 29 (14.3) | 40 (16.6) | 0.503 |
| Carotid Artery Stenosis | 12 (6.6) | 2 (1.4) | 0.022* | 26 (12.8) | 18 (7.5) | 0.061 |
| Peripheral Vascular Disease | 14 (7.7) | 12 (8.4) | 0.818 | 19 (9.4) | 24 (10.0) | 0.832 |
| History of Smoking | 60 (33.0) | 33 (23.1) | 0.050* | 45 (22.2) | 38 (15.8) | 0.085 |
| Diabetes | 64 (35.2) | 48 (33.6) | 0.763 | 76 (37.4) | 105 (43.6) | 0.190 |
| Medication History: No. (%) | ||||||
| Antiplatelet | 129 (70.9) | 86 (60.1) | 0.042* | 133 (65.5) | 164 (68.0) | 0.572 |
| Antihypertension | 157 (86.3) | 128 (89.5) | 0.376 | 163 (80.3) | 203 (84.2) | 0.278 |
| Cholesterol Reducer | 146 (80.2) | 106 (74.1) | 0.191 | 154 (75.9) | 182 (75.5) | 0.933 |
| Diabetes Medication | 48 (26.4) | 43 (30.1) | 0.461 | 60 (29.6) | 80 (33.2) | 0.411 |
| Initial NIH Stroke Scale Group: No. (%) | ||||||
| 0-9 | 119 (65.4) | 84 (58.7) | 0.616 | 158 (77.8) | 159 (66.0) | 0.026* |
| 10-14 | 24 (13.2) | 20 (14.0) | 19 (9.4) | 27 (11.2) | ||
| 15-20 | 21 (11.5) | 20 (14.0) | 12 (5.9) | 31 (12.9) | ||
| 21-25 | 18 (9.9) | 19 (13.3) | 14 (6.9) | 24 (10.0) | ||
| Mean ± SD | 9.00±6.6 | 9.97±6.8 | 0.197 | 6.33±6.2 | 8.24±6.8 | 0.002* |
| Risk of Mortality GWTG Ischemic Stroke: | ||||||
| Mean ± SD | 5.35±5.9 | 5.59±6.1 | 0.727 | 4.04±4.9 | 5.09±5.5 | 0.046* |
| Body Mass Index | ||||||
| Mean ± SD | 28,6±5.8 | 29.7±7.6 | 0.153 | 28.0±5.7 | 29.2±8.3 | 0.080 |
Continuous variables are represented as Mean ± S.D. and comparisons between groups were determined using Student’s T Test. Discrete variables are represented as Count (Percent Frequency) and comparisons between rtPA and non rtPA groups were made using Pearson’s Chi-Squared