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. 2019 Jan 17;9:11. doi: 10.1186/s13578-019-0273-3

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Effects of rhein and allopurinol on renal dysfunction induced by adenine in rats. Parameters of renal dysfunction: serum uric acid (Sur), serum creatinine (Scr), blood urea nitrogen (BUN), 24 h-proteinuria and serum β2-microglobulin (β2-MG) level. **P < 0.01 vs. control; ^#P < 0.05, ^##P < 0.01 vs. UAN group