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. 2019 Jan 17;9:11. doi: 10.1186/s13578-019-0273-3

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effects of rhein on levels of inflammation factors and ANRIL in UAN rats. a ELISA analysis of TNF-α, IL-1β, IL-6 and IL-8 in serum. b qRT-PCR analysis of ANRIL, IL-6 and IL-8 in the kidneys of UAN rats. **P < 0.01 vs. control; ^##P < 0.01 vs. UAN group