| SclP (213) WP_037773640.1
|
4-Phosphopantetheinyl transferase (54/61) Streptomyces pristinaespiralis WP_078951206.1
|
PPTase |
Biosynthesis of the glycolic acid unit |
| SclQ4 (386) WP_030624999.1
|
QncL (37/49) Streptomyces melanovinaceus AFJ11255.1 (ref. 34) |
Lipoyl attachment domain, acyltransferase catalytic domain |
| SclQ3 (338) WP_030625001.1
|
QncL (51/68) S. melanovinaceus AFJ11255.1 (ref. 34) |
Pyrimidine binding domain, transketolase C-terminal domain |
| SclQ2 (305) WP_078889003.1
|
QncN (61/73) S. melanovinaceus AFJ11257.1 (ref. 34) |
ThDP binding domain |
| SclQ1 (76) WP_030625009.1
|
QncM (32/68) S. melanovinaceus AFJ11256.1 (ref. 34) |
Acyl carrier protein (ACP) |
|
|
| SclM1 (200) WP_078889004.1
|
MmfR (56/73) Streptomyces coelicolor A3(2) WP_011039544.1 (ref. 9 and 10) |
TetR-family transcriptional repressor |
Regulation of the expression of scleric acid biosynthetic genes |
| SclM2 (336) WP_078889005.1
|
MmfL (35/47) S. coelicolor A3(2) WP_011039545.1 (ref. 9 and 10) |
Signaling molecule biosynthesis (butenolide synthase) |
| SclL (106) WP_051872433.1
|
LysR family transcriptional regulator (61/72) S. venezuelae WP_015035381.1
|
LysR transcriptional regulator |
| SclM3 (228) WP_078889008.1
|
MmfP (46/56) S. coelicolor A3(2) WP_011039547.1 (ref. 9 and 10) |
Signaling molecule biosynthesis (hydrolase) |
| SclM4 (196) WP_051872434.1
|
MmyR (41/56) S. coelicolor A3(2) WP_011039548.1 (ref. 9 and 10) |
TetR-family transcriptional repressor |
| SclM5 (378) WP_051872435.1
|
MmfH (49/59) S. coelicolor A3(2) WP_011039546.1 (ref. 9 and 10) |
Signaling molecule biosynthesis (oxidoreductase) |
|
|
| SclN (1083) WP_078889006.1
|
PuwA (32/48) Cylindrospermum alatosporum CCALA 988 AIW82277.1 (ref. 32) |
NRPS [C-A-PCP] |
Activation of l-proline and condensation with glycolic acid |
|
|
| SclT (243) WP_030625041.1
|
Thioesterase (45/56) Streptomyces sviceus WP_007379259.1
|
Thioesterase (TE) |
Hydrolytic release of scleric acid from a carrier protein |
|
|
| SclA (656) WP_051872438.1
|
PauY18 (56/67) Streptomyces sp. YN86 AIE54238.1 (ref. 33) |
Anthranilate synthase |
Biosynthesis of the benzoic acid unit |
| SclD (405) WP_030625030.1
|
PauY21 (55/65) Streptomyces sp. YN86 AIE54241.1 (ref. 33) |
DAHP synthase |
| SclI (220) WP_030625033.1
|
PauY19 (57/71) Streptomyces sp. YN86 AIE54239.1 (ref. 33) |
Isochorismatase |
|
|
| SclG (439) WP_030625035.1
|
ATP-grasp domain-containing protein (49/62) Streptomyces sp. NRRL B-5680 WP_051746523.1
|
ATP-grasp family enzyme |
Condensation reaction of the proline unit with benzoic acid |
|
|
| SclE (435) |
Major Facilitator Superfamily transporter (53/65) Amycolatopsis vancoresmycina WP_003090471.1
|
MFS transporter |
Export of scleric acid outside the cell |
