Table 1:
Top 15 most biologically significant proteins from the most abundant exosomal proteins identified by proteomics analysis on asbestos exposed mice compared to non-exposed mice.
| Accession # | Description | Fold Change | p-value |
|---|---|---|---|
| Q61646 | Haptoglobin | 3.559 | 0.232 |
| O70456 | 14-3-3 protein sigma | 3.401 | 0.415 |
| Q5FW60 | Major urinary protein 20 | 3.075 | 0.188 |
| Q8K0E8 | Fibrinogen beta chain | 3.058 | 0.172 |
| Q91X70 | Complement component 6 | 3.014 | 0.151 |
| Q91X72 | Hemopexin | 2.592 | 0.235 |
| Q91V57-3 | Isoform 3 of N-chimaerin | 2.280 | 0.034 |
| Q08879-2 | Isoform C of Fibulin-1 | 2.248 | 0.160 |
| Q61147 | Ceruloplasmin (Splice Variant 2) | 2.169 | 0.199 |
| G3X9T8 | Ceruloplasmin (Splice Variant 1) | 2.166 | 0.198 |
| Q3V3K3 | Putative uncharacterized protein | 1.942 | 0.044 |
| Q08879 | Fibulin-1 | 1.801 | 0.227 |
| P19091 | Androgen receptor | 1.642 | 0.047 |
| E9Q5F6 | Polyubiquitin-C (Fragment) | 1.549 | 0.030 |
| Q5U405 | Transmembrane protease serine 13 | 1.493 | 0.020 |