Table 1.
Results obtained by miRNet analysis.
| Deregulated proteins | microRNAs (gene symbols; gene IDs) |
|---|---|
| VL Over-expressed | miR-484 |
| miR-92a-3p | |
| miR-16-5p | |
| miR-615-3p | |
| miR-222-3p | |
| miR-320a | |
| VL Over-expressed in muscle | let-7a-5p (EEF2; ID: 1938; eukaryotic translation elongation factor 2) (VCL; ID: 7414; vinculin) |
| miR-125b-5p (VDAC1; ID: 7416; voltage dependent anion channel 1) (VCL; ID: 7414; vinculin) | |
| VL Down-expressed | miR-5196-5p |
| miR-4747-5p | |
| VL Down-expressed in muscle | miR-1-3p (SUCLA2; ID: 8803; succinate-CoA ligase ADP-forming beta subunit) (PRDX2; ID: 7001; peroxiredoxin 2) |
| miR-125b-5p (PRDX2; ID: 7001; peroxiredoxin 2) | |
| SOL Over-expressed | miR-222-3p |
| miR-let-7b-5p | |
| miR-34a-5p | |
| miR-320a | |
| SOL Over-expressed in muscle | let-7a-5p (VCL; ID: 7414; vinculin) miR-125b-5p (VCL; ID: 7414; vinculin) |
| SOL Down-expressed | miR-30c-5p |
| miR-1-3p | |
| miR-30a-5p | |
| SOL Down-expressed in muscle | miR-1-3p (SUCLA2; ID: 8803; succinate-CoA ligase ADP-forming beta subunit) (ACTC1; ID: 70; actin, alpha, cardiac muscle 1) miR-95-5p (ACTC1; ID: 70; actin, alpha, cardiac muscle 1) |
We reported the putative microRNAs that are associated to the over- and down-expressed VL/SOL proteins (genes). The genes associated to muscle tissue are also reported in parenthesis (bold). VL, vastus lateralis human muscle; SOL, human soleus.