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. 2019 Jan 14;11:13–22. doi: 10.2147/HMER.S164250

Table 4.

Summary of recommendations of empirical antibiotic treatment of spontaneous bacterial peritonitis according to the guidelines of the European Association for the Study of the Liver

Type of infection Empirical antibiotic regimen

Community acquireda Third-generation cephalosporin or piperacillin-tazobactam
Healthcare associatedb A) Piperacillin-tazobactam in patients without sepsis and in areas with low prevalence of multidrug resistant bacteria.
B) Consider treatment as nosocomial if high prevalence of multidrug resistant bacteria or sepsis.
Nosocomialc Carbapenems alone or with daptomycin, vancomycin, or linezolid if high prevalence of multidrug-resistant bacteria, gram-positive bacteriea or sepsis

Notes: Data from European Association for the Study of the Liver.3

a

Infection diagnosed at the time of admission or in the first 48 hours in patients who do not meet criteria for healthcare-associated infection.

b

Infection diagnosed at the time of admission or in the first 48 hours in patients that in the previous 90 days had contact with the hospital (dialysis, paracentesis, endoscopy, etc) or that they live in a residence.

c

Infection diagnosed in hospitalized patients after 48 hours, or infection diagnosed at admission or in the first 48 hours in patients who have been hospitalized for at least 2 days in the past 90 days.