Table 3.
Sensitivity, specificity, PPV and NPV of IBP for the diagnosis of axSpA
| Assessor | IBP according to… | Sensitivity, % (95% CI) | Specificity, % (95% CI) | PPV (95% CI) |
NPV (95% CI) |
LR+ (95% CI) |
LR− (95% CI) |
| Blinded rheumatologist | Global evaluation | 81.1 (75.4 to 86.8) |
43.9 (37.3 to 50.7) |
53.9 (48.0 to 59.8) |
74.2 (66.8 to 81.7) |
1.4 (1.3 to 1.7) |
0.4 (0.3 to 0.6) |
| Calin’s criteria | 79.4 (73.5 to 85.4) |
25.1 (19.6 to 31.3) |
46.1 (40.6 to 51.9) |
60.2 (50.0 to 70.2) |
1.1 (1.0 to 1.2) |
0.8 (0.6 to 1.2) |
|
| Berlin criteria | 81.1 (75.4 to 86.8) |
32.3 (26.2 to 38.6) |
49.2 (43.3 to 55.0) |
67.9 (58.7 to 76.7) |
1.2 (1.1 to 1.3) |
0.6 (0.4 to 0.8) |
|
| ASAS criteria | 74.4 (68.1 to 80.8) |
39.5 (33.0 to 46.1) |
49.8 (43.8 to 55.8) |
65.7 (57.3 to 73.4) |
1.2 (1.1 to 1.4) |
0.6 (0.5 to 0.9) |
|
| Diagnosing rheumatologist | Global evaluation | 90.0 (85.6 to 94.4) |
58.7 (52.1 to 65.2) |
63.8 (57.8 to 69.7) |
87.9 (81.9 to 92.7) |
2.2 (1.9 to 2.6) |
0.2 (0.1 to 0.3) |
| Calin’s criteria | 85.0 (79.8 to 90.2) |
26.9 (21.4 to 33.0) |
48.4 (42.8 to 54.1) |
69.0 (58.4 to 78.2) |
1.2 (1.1 to 1.3) |
0.6 (0.4 to 0.8) |
|
| Berlin criteria | 83.9 (78.5 to 89.3) |
44.8 (38.2 to 51.6) |
55.1 (49.0 to 61.1) |
77.5 (69.7 to 84.4) |
1.5 (1.3 to 1.7) |
0.4 (0.2 to 0.5) |
|
| ASAS criteria | 83.9 (78.5 to 89.3) |
35.4 (29.2 to 41.8) |
51.2 (45.3 to 57.0) |
73.2 (64.2 to 80.8) |
1.3 (1.2 to 1.5) |
0.5 (0.3 to 0.7) |
|
| Patient | Calin’s criteria | 75.1 (68.8 to 81.5) |
20.6 (15.6 to 26.3) |
43.3 (37.7 to 49.0) |
50.6 (39.8 to 61.0) |
0.9 (0.8 to 1.1) |
1.2 (0.8 to 1.7) |
| Berlin criteria | 86.4 (81.4 to 91.5) |
18.3 (13.5 to 23.7) |
46.1 (40.6 to 51.6) |
62.5 (50.0 to 74.0) |
1.1 (1.0 to 1.2) |
0.7 (0.5 to 1.2) |
|
| ASAS criteria | 74.0 (67.6 to 80.5) |
31.1 (25.0 to 37.6) |
46.5 (40.5 to 52.4) |
59.7 (50.5 to 68.7) |
1.1 (0.9 to 1.2) |
0.8 (0.6 to 1.1) |
ASAS, Assessment of SpondyloArthritis international Society; IBP, inflammatory back pain; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; SpA, spondyloarthritis; axSpA, axial spondyloarthritis.