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. 2018 Dec 5;4(2):e000825. doi: 10.1136/rmdopen-2018-000825

Table 3.

Sensitivity, specificity, PPV and NPV of IBP for the diagnosis of axSpA

Assessor IBP according to… Sensitivity, % (95% CI) Specificity, % (95% CI) PPV
(95% CI)
NPV
(95% CI)
LR+
(95% CI)
LR−
(95% CI)
Blinded rheumatologist Global evaluation 81.1
(75.4 to 86.8)
43.9
(37.3 to 50.7)
53.9
(48.0 to 59.8)
74.2
(66.8 to 81.7)
1.4
(1.3 to 1.7)
0.4
(0.3 to 0.6)
Calin’s criteria 79.4
(73.5 to 85.4)
25.1
(19.6 to 31.3)
46.1
(40.6 to 51.9)
60.2
(50.0 to 70.2)
1.1
(1.0 to 1.2)
0.8
(0.6 to 1.2)
Berlin criteria 81.1
(75.4 to 86.8)
32.3
(26.2 to 38.6)
49.2
(43.3 to 55.0)
67.9
(58.7 to 76.7)
1.2
(1.1 to 1.3)
0.6
(0.4 to 0.8)
ASAS criteria 74.4
(68.1 to 80.8)
39.5
(33.0 to 46.1)
49.8
(43.8 to 55.8)
65.7
(57.3 to 73.4)
1.2
(1.1 to 1.4)
0.6
(0.5 to 0.9)
Diagnosing rheumatologist Global evaluation 90.0
(85.6 to 94.4)
58.7
(52.1 to 65.2)
63.8
(57.8 to 69.7)
87.9
(81.9 to 92.7)
2.2
(1.9 to 2.6)
0.2
(0.1 to 0.3)
Calin’s criteria 85.0
(79.8 to 90.2)
26.9
(21.4 to 33.0)
48.4
(42.8 to 54.1)
69.0
(58.4 to 78.2)
1.2
(1.1 to 1.3)
0.6
(0.4 to 0.8)
Berlin criteria 83.9
(78.5 to 89.3)
44.8
(38.2 to 51.6)
55.1
(49.0 to 61.1)
77.5
(69.7 to 84.4)
1.5
(1.3 to 1.7)
0.4
(0.2 to 0.5)
ASAS criteria 83.9
(78.5 to 89.3)
35.4
(29.2 to 41.8)
51.2
(45.3 to 57.0)
73.2
(64.2 to 80.8)
1.3
(1.2 to 1.5)
0.5
(0.3 to 0.7)
Patient Calin’s criteria 75.1
(68.8 to 81.5)
20.6
(15.6 to 26.3)
43.3
(37.7 to 49.0)
50.6
(39.8 to 61.0)
0.9
(0.8 to 1.1)
1.2
(0.8 to 1.7)
Berlin criteria 86.4
(81.4 to 91.5)
18.3
(13.5 to 23.7)
46.1
(40.6 to 51.6)
62.5
(50.0 to 74.0)
1.1
(1.0 to 1.2)
0.7
(0.5 to 1.2)
ASAS criteria 74.0
(67.6 to 80.5)
31.1
(25.0 to 37.6)
46.5
(40.5 to 52.4)
59.7
(50.5 to 68.7)
1.1
(0.9 to 1.2)
0.8
(0.6 to 1.1)

ASAS, Assessment of SpondyloArthritis international Society; IBP, inflammatory back pain; LR, likelihood ratio; NPV, negative predictive value; PPV, positive predictive value; SpA, spondyloarthritis; axSpA, axial spondyloarthritis.