Table 3.
Comparison Of Clinical Parameters By Treatment Group At Baseline Visit And Day 42
| Parameters (Normal Range for Age) | Baseline- Pre Treatment (Mean + SD) | Day 42 - Post Treatment (Mean + SD) | ||||
|---|---|---|---|---|---|---|
| LR (n=13) | Placebo (n=7) | P value | LR (n=10) | Placebo (n=5) | P value | |
| HGB | 11.6±1.5 | 11.7±1.2 | 0.92t | 11.4±1.0 | 11.0±0.7 | 0.42t |
| HCT | 34.0±5.0 | 34.5±4.2 | 0.83t | 33.6±3.4 | 31.8±2.0 | 0.30t |
| WBC | 8.1±1.8 | 10.4±2.9 | 0.03t | 9.7±2.5 | 10.6±2.5 | 0.47t |
| ANC | 1.4±0.5 | 2.4±1.4 | 0.10t | 2.5±1.8 | 1.7±0.7 | 0.35t |
| LYMPHOCYTES (%) | 68.4±9.7 | 66.5±11.6 | 0.69t | 66.6±14.3 | 76.6±9.4 | 0.18t |
| EOSINOPHILS (%) | 5.5±3.4 | 4.1±1.6 | 0.30t | 3.3±1.5 | 3.2±2.2 | 0.96t |
| PLATELETS | 421.2±154.5 | 392.1±117.1 | 0.66t | 439.2±120.3 | 481.8±129.9 | 0.53t |
| CRP | 2.4±1.1 | 2.1±1.3 | 0.63t | 2.3±1.8 | 2.9±0.0 | 0.36t |
| SGOT | 41.1±15.1 | 43.0±22.6 | 0.82t | 44.2±13.9 | 40.8±11.7 | 0.64t |
| SGPT | 43.6±14.5 | 39.4±13.5 | 0.53t | 44.1±15.1 | 44.2±12.9 | 0.99t |
| BILIRUBIN | 2.4±3.2 | 3.6±3.9 | 0.45t | 0.7±1.0 | 0.5±0.3 | 0.64t |
| BLOOD UREA NITROGEN | 5.2±1.4 | 6.7±2.7 | 0.10t | 5.8±2.9 | 5.8±1.9 | 1.00t |
| CREATININE | 0.3±0.1 | 0.2±0.1 | 0.53t | 0.2±0.1 | 0.3±0.1 | 0.56t |
| BICARBONATE | 22.5±2.2 | 22.1±3.4 | 0.80t | 24.8±5.8 | 22.2±0.8 | 0.19t |
t
denotes p-values obtained by two sample t-test