Figure 7.

Effects of nicotine on mouse decision-making among reward sizes. (A) Illustration of the modeling of the task. Three explicit locations are placed in an open field. Mice receive a reward each time they reach one of the locations. Simulated mice, who could not receive two consecutive rewards at the same location, alternate between rewarding locations. The probability of transition from one state to another depends on the two available options. (B) Proportion of choices of the three rewarding locations as a function of reward value (2, 4, 8 μL) over 10,000 simulations in control mice (blue) or nicotine-ingested mice (red).