Table 2. Click reactions of UiO-67 and UiO-67 modified by post synthetic exchange to include L-N3 and L-C C appended linkers. Clicked products detected by 1H NMR of post-reaction digested MOF.
| (A) Single click reactions | ||||
| Linkers | CuI? | Reactants | Observed clicked products | Yield |
| Native only | Y |
|
None | — |
| L-N3 | Y | — | None | — |
| L-N3 | N |
|
None | — |
| L-N3 | Y |
|
|
46% |
| L-C C | Y | — | None | — |
| L-C C | N |
|
None | — |
| L-C C | Y |
|
|
59% |
| L-N3 & L-C C | Y | — | None | — |
| (B) Double click reaction | ||||
| Linkers | Step | Reactants | Observed clicked products | Yield |
| L-N3 & L-C C | (1) |
|
|
50% |
| (2) |
|
50% | ||