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. Author manuscript; available in PMC: 2019 Jan 17.
Published in final edited form as: Sci Transl Med. 2018 Jun 13;10(445):eaaq1240. doi: 10.1126/scitranslmed.aaq1240

Figure 2. Dynamic BH3 profiling predicts sensitization to venetoclax by simvastatin.

Figure 2.

Dynamic BH3 profiles for all cells treated with 10 µM simvastatin or 50 nM BEZ235 for 16 hours. Significance testing was performed by two-tailed paired Student’s t-test relative to vehicle-treated control samples; n = 4 (OCI-LY8) or 3 (SU-DHL4, OCI-LY1).