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. 2018 Sep 19;8(3):91–165. doi: 10.1016/j.kisu.2018.06.001

Table 9.

Hierarchy of outcomes

Hierarchy Outcome
Critical importance Mortality, graft loss, ESKD
High importance SVR, treatment discontinuation due to adverse events, serious adverse events, CKD incidence, quality of life, HCV seroconversion, test performance characteristics
Moderate importance HCV relapse, kidney function, proteinuria, HCV positivity, hepatocellular carcinoma

CKD, chronic kidney disease; ESKD, end-stage kidney disease; HCV, hepatitis C virus; SVR, sustained virologic response.