(A) ROC curve when staining intensity in adipose tissue was applied to predict tumor grade (OR = 1.01, AUC = 0.57); (B) ROC curve when proportion of positive GRP78 staining in adipose tissue was applied to predict tumor grade (OR = 1.00, AUC = 0.52); (C) ROC curve when staining intensity in adipose tissue was applied to predict tumor size (OR = 1.08, AUC = 0.63); (D) ROC curve when proportion of positive GRP78 staining in adipose tissue was applied to predict tumor size (OR = 0.99, AUC = 0.49); (E) ROC curve when staining intensity in adipose tissue was applied to predict whether there is a presence of distant metastasis (OR = 1.17, AUC = 0.73); (F) ROC curve when proportion of positive GRP78 staining in adipose tissue was applied to predict whether there is a presence of distant metastasis (OR = 1.06, AUC = 0.55). Abbreviations: AUC, area under the curve; ccRCC, clear cell renal cell carcinoma; OR, odds ratio; ROC, receiver operating characteristics.