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. 2019 Jan 17;14(1):e0210246. doi: 10.1371/journal.pone.0210246

Table 3. Distribution of GRP78 expression in ccRCC tumor tissue (N = 114) among different categories of ccRCC aggressiveness.

ccRCC aggressiveness categories N Staining intensity 95% CI Proportion of positive pixels 95% CI
Tumor grade
Grade1 13 202.6 [201.2,204.0] 0.49 [0.42,0.56]
Grade2 43 202.5 [201.6,203.3] 0.47 [0.44,0.51]
Grade3 42 201.8 [200.7,202.9] 0.49 [0.45,0.53]
Grade4 16 202.9 [200.7,205.0] 0.45 [0.39,0.51]
Tumor stagea
Stage 1 64 202.4 [201.7,203.1] 0.47 [0.44,0.50]
Stage 2 7 201.8 [199.7,203.9] 0.47 [0.40,0.53]
Stage 3 39 202.6 [201.5,203.8] 0.48 [0.44,0.52]
Stage 4 3 196.3 [183.7,208.8] 0.53 [0.26,0.84]
Tumor size
≤70mm 86 202.3 [201.7,203.0] 0.47 [0.45,0.50]
>70mm 28 202.2 [200.8,203.5] 0.49 [0.45,0.54]
Distant metastasisa
No distant metastasis 104 202.22 [201.7,202.8] 0.48 [0.45,0.50]
Presence of distant metastasis 9 203.1 [198.3,207.8] 0.49 [0.38,0.59]

aMissing data <1%