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. 2019 Jan 17;14(1):e0210466. doi: 10.1371/journal.pone.0210466

Table 2. Domains of personality, depression and anxiety scores between study groups.

pSS patients
N = 105
(Mean, 95% CI)
RA patients
N = 52
(Mean, 95% CI)
Healthy Controls
N = 54
(Mean, 95% CI)
Effect size
D
p* pa
Neuroticism 94.76 (90.66–98.87) 95.56 (90.85–100.27) 84.63 (78.46–90.80)# 0.46 0.007 0.422
Extraversion 94.79 (91.55–98.03) 92.15 (87.87–96.44) 104.20 (98.67–109.73)# 0.51 0.001* 0.206
Openness to experience
101.86 (97.95–105.77) 102.69 (97.52–107.87) 111.17 (106.23–116.11)# 0.65 0.013* 0.858
Agreeableness 120.48 (118.06–122.89) 121.37 (117.13–125.60) 121.04 (117.65–124.42) 0.05 0.916 0.999
Conscientiousness 122.97 (119.77–126.17) 121.00 (116.29–125.71) 125.02 (120.30–129.74) 0.12 0.471 0.481
SDS 56.75 (55.55–57.94) 54.90 (53.22–56.58) 55.48 (53.76–57.21) 0.20 0.171 0.051
SAS 37.53 (35.50–39.56) 38.63 (35.93–41.33) 30.48 (28.20–32.77)# 0.74 <0.001 0.466

*according to one way ANOVA

#differences between means of Sjogren and healthy controls according to multiple comparisons Bonferroni test

d—Cohen`s d as the measure of effect size (pSS patients vs. Healthy controls)

paaccording to ANCOVA between pSS and RA patients with disease duration as potential confound