Table 1. Correlation between gene levels and clinical variables as determined in the uveal melanoma samples from the TGCA cohort of patients.
Control Variables | OS | PFS | MitoticCount | BasalDiameter | Thickness | HLAA | HLAB | HLAC | HLAF | HLAG | HLAH | HLADMA | HLADMB | HLADOA | HLADOB | HLADPA | HLADQA1 | HLADQB1 | HLADRA | PDL1 | PDL2 | B7H3 | TNFRSF6B | GAL9 | CD47 | CD200 | HVEM | CD155 | ||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DiseaseStatus & HistoType & Adjuvant & BAP1MUT | OS | Correlation | 1.000 | 0.983 | 0.014 | 0.127 | 0.243 | -0.494 | -0.352 | -0.347 | -0.239 | -0.226 | -0.458 | -0.278 | -0.291 | -0.289 | -0.192 | -0.312 | -0.309 | -0.284 | -0.281 | -0.376 | -0.170 | 0.038 | -0.047 | -0.107 | -0.101 | 0.232 | -0.105 | 0.112 |
Significance (2-tailed) | 0.000 | 0.935 | 0.441 | 0.136 | 0.001 | 0.028 | 0.030 | 0.143 | 0.166 | 0.003 | 0.086 | 0.072 | 0.074 | 0.241 | 0.053 | 0.056 | 0.080 | 0.083 | 0.018 | 0.301 | 0.820 | 0.776 | 0.518 | 0.540 | 0.155 | 0.523 | 0.498 | |||
PFS | Correlation | 0.983 | 1.000 | -0.006 | 0.123 | 0.254 | -0.484 | -0.364 | -0.373 | -0.254 | -0.219 | -0.453 | -0.286 | -0.306 | -0.313 | -0.192 | -0.322 | -0.301 | -0.280 | -0.294 | -0.395 | -0.171 | 0.040 | -0.019 | -0.111 | -0.162 | 0.195 | -0.119 | 0.092 | |
Significance (2-tailed) | 0.000 | 0.973 | 0.456 | 0.119 | 0.002 | 0.023 | 0.019 | 0.119 | 0.181 | 0.004 | 0.077 | 0.059 | 0.053 | 0.243 | 0.046 | 0.063 | 0.084 | 0.069 | 0.013 | 0.297 | 0.808 | 0.907 | 0.501 | 0.323 | 0.235 | 0.470 | 0.578 | |||
MitoticCount | Correlation | 0.014 | -0.006 | 1.000 | 0.287 | 0.292 | -0.031 | -0.036 | -0.081 | -0.107 | 0.057 | 0.038 | 0.037 | -0.084 | -0.111 | -0.087 | -0.027 | 0.069 | 0.015 | -0.067 | -0.196 | -0.183 | -0.036 | -0.181 | -0.014 | -0.069 | -0.107 | -0.006 | 0.253 | |
Significance (2-tailed) | 0.935 | 0.973 | 0.077 | 0.071 | 0.852 | 0.830 | 0.622 | 0.517 | 0.731 | 0.817 | 0.821 | 0.611 | 0.503 | 0.597 | 0.872 | 0.675 | 0.930 | 0.685 | 0.231 | 0.266 | 0.827 | 0.270 | 0.934 | 0.677 | 0.518 | 0.972 | 0.120 | |||
BasalDiameter | Correlation | 0.127 | 0.123 | 0.287 | 1.000 | 0.512 | -0.127 | -0.026 | -0.149 | -0.027 | -0.055 | -0.073 | 0.028 | -0.034 | -0.084 | -0.025 | -0.081 | -0.015 | -0.013 | -0.047 | -0.148 | -0.068 | 0.024 | 0.225 | 0.171 | -0.110 | 0.004 | -0.090 | 0.316 | |
Significance (2-tailed) | 0.441 | 0.456 | 0.077 | 0.001 | 0.440 | 0.874 | 0.365 | 0.868 | 0.740 | 0.658 | 0.866 | 0.840 | 0.612 | 0.880 | 0.622 | 0.926 | 0.938 | 0.775 | 0.369 | 0.682 | 0.886 | 0.168 | 0.298 | 0.505 | 0.979 | 0.587 | 0.050 | |||
Thickness | Correlation | 0.243 | 0.254 | 0.292 | 0.512 | 1.000 | -0.137 | -0.062 | -0.114 | -0.154 | -0.153 | -0.001 | -0.074 | -0.148 | -0.187 | -0.185 | -0.120 | -0.075 | -0.124 | -0.149 | -0.367 | -0.298 | -0.089 | 0.078 | 0.184 | -0.164 | 0.025 | -0.047 | 0.204 | |
Significance (2-tailed) | 0.136 | 0.119 | 0.071 | 0.001 | 0.406 | 0.706 | 0.490 | 0.350 | 0.351 | 0.997 | 0.653 | 0.369 | 0.254 | 0.259 | 0.467 | 0.650 | 0.452 | 0.364 | 0.021 | 0.065 | 0.590 | 0.635 | 0.263 | 0.317 | 0.880 | 0.777 | 0.213 |