Table 4. For Kaplan-Meier analysis, predicted values of the genes of interest were generated using General Linear Model to account for clinical confounding variables and were dichotomized using median value as cut-off.

For each gene, Log-rank (Mantel-Cox) analysis was performed to assess statistical differences in Progression-Free Survival time between patients with Low and High expression.

		Estimate	Std. Error	95% Confidence Interval		Log Rank (Mantel-Cox)
				Lower Bound	Upper Bound	Chi-Square	Sig.
HLAA_predicted	Low expression	60.849	10.617	40.040	81.658	5.316044951	0.021129918
	High expression	33.412	4.032	25.509	41.315
HLAB_predicted	Low expression	55.946	10.201	35.952	75.939	0.869944517	0.350970669
	High expression	37.788	3.113	31.685	43.890
HLAC_predicted	Low expression	55.442	10.217	35.417	75.468	0.651291391	0.419651352
	High expression	37.976	2.947	32.201	43.751
HLAF_predicted	Low expression	53.142	9.316	34.883	71.400	0.171876007	0.678449895
	High expression	36.567	2.563	31.544	41.589
HLAG_predicted	Low expression	77.906	4.068	69.933	85.880	5.92839856	0.014898775
	High expression	36.197	4.697	26.991	45.403
HLAH_predicted	Low expression	61.117	10.602	40.337	81.897	5.989849457	0.01438843
	High expression	32.887	4.265	24.528	41.246
HLADMA_predicted	Low expression	52.667	9.338	34.365	70.970	0.082972562	0.773308785
	High expression	36.747	2.424	31.996	41.498
HLADMB_predicted	Low expression	52.146	9.366	33.789	70.503	0.002775545	0.957984135
	High expression	37.265	2.248	32.858	41.672
HLADOA_predicted	Low expression	55.442	10.217	35.417	75.468	0.651291391	0.419651352
	High expression	37.976	2.947	32.201	43.751
HLADOB_predicted	Low expression	50.167	9.126	32.281	68.054	0.389689022	0.53246291
	high expression	39.300	1.184	36.979	41.621
HLADPA_predicted	Low expression	54.889	10.239	34.820	74.958	0.470277913	0.492859343
	High expression	38.138	2.806	32.638	43.638
HLADQA1_predicted	Low expression	57.875	10.408	37.476	78.274	2.255889815	0.133106926
	high expression	35.569	3.732	28.254	42.883
HLADQB1_predicted	Low expression	52.947	9.253	34.811	71.082	0.132323225	0.716035297
	High expression	36.112	2.963	30.304	41.920
HLADRA_predicted	Low expression	54.889	10.239	34.820	74.958	0.470277913	0.492859343
	High expression	38.138	2.806	32.638	43.638
PDL1_predicted	Low expression	58.256	10.422	37.829	78.684	2.587052616	0.107740658
	High expression	35.469	3.734	28.150	42.788
PDL2_predicted	Low expression	53.142	9.316	34.883	71.400	0.171876007	0.678449895
	High expression	36.567	2.563	31.544	41.589
B7H3_predicted	Low expression	47.795	9.010	30.135	65.454	1.235888265	0.266264959
	High expression	43.523	1.969	39.663	47.383
TNFRSF6B_predicted	Low expression	36.302	4.726	27.039	45.564	5.737360787	0.016607729
	High expression	77.909	4.072	69.927	85.892
GAL9_predicted	Low expression	37.204	4.571	28.244	46.164	4.368411636	0.036611103
	High expression	75.214	6.375	62.719	87.709
CD47_predicted	Low expression	63.613	10.808	42.430	84.796	9.483907795	0.00207282
	High expression	31.139	4.341	22.630	39.647
HVEM_predicted	Low expression	46.037	8.365	29.642	62.431	2.86334347	0.090618963
	High expression	45.926	1.856	42.289	49.563
CD155_predicted	Low expression	46.192	4.012	38.328	54.056	1.343753464	0.24637312
	High expression	47.095	10.294	26.920	67.271