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(A) Distribution of mutation types in PRECAMA samples is compared with those observed in women 45 years old or younger selected from the TCGA and METABRIC BC series [19, 20] or the IARC TP53 Database [21]. (B) IHC subtype distributions of PRECAMA samples in each mutation type category. Luminal A: ER+/HER2-; luminal B: ER+/HER2+; HER2-enriched: ER-/HER2+; triple-negative: ER-/PR-/HER2-.
