Parameters | Non-responders No. of oocytes = 0 (n = 14) |
Poor-responders No. of oocytes = 1 – 5 (n = 18) |
Normo-responders No. of oocytes = 6 – 10 (n = 30) |
High-responders No. of oocytes > 10 (n = 28) |
---|---|---|---|---|
FSH: follicle-stimulating hormone; ADM2: adrenomedullin 2; VEGF: vascular endothelial growth factor; sFlt-1: soluble Fms-like tyrosine kinase-1; sVEGFR-2: soluble VEGF receptor 2 Significant differences (p < 0.05) compared with a non-responders, b poor-responders. | ||||
Age (years) | 29 ± 8.64 | 34.07 ± 6.87 | 31.16 ± 4.44 | 30.28 ± 4.613 |
Total dose of FSH (IU) | 1884.50 ± 1067.87 | 2270.31 ± 715.78 | 2055.06 ± 613.52 | 2040.35 ± 574.37 |
ADM2 (pg/ml) | 282.60 ± 217.34 | 41.69 ± 9.68 a | 45.38 ± 10.75 a | 46.25 ± 7.65 a |
VEGF (pg/ml) | 1452.25 ± 580.74 | 1066.6 ± 218.02 a | 1363.1 ± 700.76 | 1228.9 ± 421.06 |
sFlt-1 (ng/ml) | 473.93 ± 426.19 | 536.87 ± 211.82 | 364.01 ± 258.04 b | 375.11 ± 230.02 b |
sVEGFR-2 (ng/ml) | 8.38 ± 5.7 | 4.24 ± 1.82 a | 4.66 ± 3.13 | 5.38 ± 3.83 |
VEGF/sFlt-1 | 2.98 ± 1.82 | 1.98 ± 0.94 | 3.38 ± 2.27 | 3.33 ± 2.01 |
VEGF/sVEGFR-2 | 204.72 ± 68.51 | 265.29 ± 55.97 | 322.10 ± 188.13 a | 266.4 ± 67.21 |