Table 3.
Characteristics of Patients Identified by Each VPS Screening Algorithm
| Population Characteristic | Sepsis Registry (n=401) | Explicit Codes (n=515) | Martin Codes (n=970) | Angus Codes (n=1387) |
|---|---|---|---|---|
| Prevalence of Severe Sepsis / Septic Shocka | 5.4% | 6.9% | 13.0% | 18.6% |
| Age in years, median (IQR) | 7 (2–14) | 7 (2–14) | 7 (2–14) | 5 (1–12) |
| Admitted from inpatient unit, n (%) | 99 (25) | 140 (27) | 275 (28) | 375 (27) |
| PIM-2 risk of mortality, median (IQR) | 2.9 (1.0–4.7) | 1.8 (1.0–4.9) | 1.3 (0.9–4.4) | 2.8 (0.9–4.2) |
| PRISM-III score, median (IQR) | 8 (4–14) | 8 (3–14) | 5 (2–11) | 3 (0–9) |
| Oncologic diagnosis, n (%) | 73 (18) | 99 (19) | 156 (16) | 128 (9) |
| Conventional mechanical ventilation, n (%) | 258 (64) | 301 (58) | 482 (50) | 826 (59) |
| Advanced mode of ventilationb, n (%) | 72 (18) | 83 (16) | 97 (10) | 127 (9) |
| Extracorporeal support, n (%) | 12 (3) | 14 (3) | 14 (1) | 18 (1) |
| PICU LOS in days, median (IQR) | 9 (3–19) | 7 (2–17) | 5 (2–13) | 6 (2–13) |
| PICU mortality, n (%) | 34 (8) | 46 (8) | 60 (6) | 64 (4) |
a
Prevalence for each method is calculated as number of patients identified divided by number of patients screened (n=7459).
b
Advanced modes of ventilation include high frequency oscillatory ventilation, volume diffusive respirator, and airway pressure release ventilation.
Abbreviations:
IQR = interquartile range; PIM = paediatric index of mortality; PRISM = pediatric risk of mortality; PICU = pediatric intensive care unit; LOS = length of stay