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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Mitochondrion. 2018 Jul 17;46:247–255. doi: 10.1016/j.mito.2018.07.004

Figure 4.

Figure 4

Interaction Box-Plots for expression of POLG2 (Geuvadis). Normalized gene expression (y-axis) is plotted by genotype/haplogroup combination in European-descent populations for rs978490. We observe a significant interaction between genotype and haplogroup, driven by a change in slope in the T haplogroup; for other groups, POLG2 expression is either equal to or slightly increasing with the number of copies of the C allele.