Fig. 2. The effect of treatment with flavonoid of Mespilus germanica leaves (10 mg/kg) on: (A) fasting glucose ^*P = 0.011, ovariectomized (OVX) + saline (SAL) group compared with sham-operated (SHAM) group, ^†P = 0.024, OVX + flavonoid (FLA) group compared with OVX+SAL group, (B) fasting insulin ^*P = 0.048, OVX+SAL group compared with SHAM group, ^†P = 0.011, OVX+FLA group compared with OVX+SAL group, (C) homeostasis model assessment estimate of insulin resistance (HOMA-IR) ^*P = 0.004, OVX+SAL group compared with SHAM group, ^†P = 0.007, OVX+FLA group compared with OVX+SAL group. Values are reported as the mean ± standard error for 8 animals per group.