Figure 2.

Reduction of the nanocapsules particle size following the injection of the organic phase over the aqueous phase. The injection of the organic phase inside the aqueous phase in the preparation of nanoemulsions (NEs) and nanocapsules (NCs) by the solvent‐displacement technique remarkably reduced the particle size compared with just pouring one phase over the other. FESEM images, using STEM (i) and InLens (ii) detectors, of the CS/lecithin/vitamin E NCs prepared by the two methods. Scale bar 200 nm. (a) Different combination of oils, surfactants and polymers were tested to produce NEs and NCs upon pouring or injecting the organic phase over the aqueous phase. (b) Differences in the particle size of the NCs and NEs obtained with this modification in the preparation procedure are shown in C. ** and *** denote significant differences between samples (p < .01 and p < .001, respectively)