Table 2.
Associations of PIP5K1α expression and clinical-pathological parameters in luminal breast cancer
| Parameters | PIP5K1α expression | Significance | |
|---|---|---|---|
| Negative/low no. (%) | Positive/high no. (%) | P value | |
| Patients’ age (years) | |||
| ≤50 | 102 (51.8) | 95 (48.2) | 0.795 |
| >50 | 207 (50.6) | 202 (49.4) | |
| Menopausal status | |||
| Premenopausal | 114 (53.0) | 101 (47.0) | 0.255 |
| Postmenopausal | 195 (49.9) | 196 (50.1) | |
| Grade | |||
| Low-grade | 66 (53.2) | 58 (46.8) | 0.031 |
| High-grade | 90 (43.5) | 117 (56.5) | |
| Tumor stage | |||
| Low-stage | 200 (53.1) | 177 (46.9) | 0.01 |
| High-stage | 12 (28.6) | 30 (71.4) | |
| NPI | |||
| Good ( < 3.4) | 128 (57.9) | 93 (42.1) | 0.004 |
| Poor ( ≥ 5.41) | 26 (36.1) | 46 (63.9) | |
NPI Nottingham Prognostic Index