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. 2018 Dec 20;4(1):75–82. doi: 10.1002/btm2.10123

Figure 2.

Figure 2

Nanoparticles localize in and around wound bed cells. Wounds on C57BL/6 mice were treated with either PBS (control) or LNPs loaded with Cy5.5‐labeled siRNA at a concentration of 5 μM. Wounds were excised 2 hr post‐treatment and stained for DNA (blue), actin (green), and the F4/80 receptor on macrophages (magenta). Nanoparticles containing siRNA (red) localized within the wound bed without clear affinity for any particular cell type. The scale bar is 15 μm