Table 1.

Measurements of the total nucleus area and nucleolar domains in µm².

Measured area (μm2)	Nucleus	Nucleolus	Heterochromatin	Euchromatin
Tet−	1.753 ± 0.112	0.475 ± 0.299	0.590 ± 0.037	0.687 ± 0.102
Tet+	2.245 ± 0.109	0.215 ± 0.073	0.590 ± 0.086	1.440 ± 0.182
Percentage change	+28%	−55%	—	+109%
Statistically different?	Yes	Yes	No	Yes

One hundred cells were measured in each one of three independent experiments. Statistics were calculated using the unpaired t test with Welch’s correction in GraphPad Prism 6 software. P values less than 0.05 were considered statistically significant.