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. 2019 Jan 17;9:160. doi: 10.1038/s41598-018-37232-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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10Panx specifically enhanced the LPS- and SAA-induced NO production. RAW264.7 cells were stimulated with LPS (1.0 μg/ml) or SAA (1.0 μg/ml) for 16 h in the absence or presence of 10Panx at indicated concentrations, and the levels of NO (Panel a) and various cytokines (Panel b) were determined by the Griess reaction or Cytokine Antibody Array, respectively. *P < 0.05 versus “−LPS” Control; ^#P < 0.05 versus “+LPS” or corresponding “+SAA” controls.