Table 1.
Characteristics at Antiretroviral Therapy (ART) Initiation and Over Follow-up of 1057 Human Immunodeficiency Virus–Infected Adults Who Initiated ART Between 2005 and 2015 in the Centers for AIDS Research Network of Integrated Clinical Systems Cohort
| Characteristic | At Antiretroviral Therapy Initiation, | Over Follow-up, |
|---|---|---|
| (n = 1057) Participants | (n = 2424) Person-Years | |
| n (%) | n (%) | |
| Time-fixed | ||
| Site | ||
| Fenway | 103 (9.7) | … |
| University of Alabama, Birmingham | 286 (27.1) | … |
| University of North Carolina, Chapel Hill | 20 (1.9) | … |
| University of California, San Diego | 427 (40.4) | … |
| University of California, San Francisco | 54 (5.1) | … |
| University of Washington | 167 (15.8) | … |
| Age in years, median (IQR) | 36 (28, 45) | … |
| Gender | ||
| Male | 929 (87.9) | … |
| Female | 128 (12.1) | … |
| Race/ethnicity | ||
| White, non-Hispanic | 509 (48.6) | … |
| Black, non-Hispanic | 288 (27.5) | … |
| Hispanic | 191 (18.2) | … |
| Other | 59 (5.6) | … |
| HIV risk group | ||
| Intravenous drug user | 109 (10.4) | … |
| Men who have sex with men | 721 (68.7) | … |
| Heterosexual | 187 (17.8) | … |
| Other | 33 (3.1) | … |
| Previous mental health diagnosis | ||
| No | 687 (65.0) | … |
| Yes | 370 (35.0) | … |
| Previous medical diagnosis | ||
| No | 941 (89.0) | … |
| Yes | 116 (11.0) | … |
| Time-updated | ||
| Depressive symptoms | ||
| No (PHQ-9, <10) | 737 (69.7) | 3755 (74.3) |
| Yes (PHQ-9, ≥ 10) | 320 (30.3) | 1299 (25.7) |
| Viral load | ||
| Undetectable (<75 copies/mL) | 0 (0.0) | 5964 (77.1) |
| Detectable (≥75 copies/mL) | 1057 (100.0) | 1769 (22.9) |
| HIV appointment status | ||
| Missed appointment | … | 2492 (17.6) |
| Kept appointment | … | 11639 (82.4) |
| Depressive symptom score (PHQ-9, range 0–27), median (IQR) | 5 (1, 11) | 4 (1, 10) |
| Panic disorder | ||
| No symptoms | 716 (68.9) | 4032 (71.5) |
| Some symptoms | 179 (17.2) | 864 (15.3) |
| Panic disorder | 145(13.9) | 746 (13.2) |
| Antidepressant prescription | ||
| Not on antidepressants | 900 (85.2) | 6101 (78.9) |
| On antidepressants | 157 (14.9) | 1632 (21.1) |
| Drug use | ||
| No current use | 437 (46.2) | 2676 (50.2) |
| Current use | 218 (23.0) | 998 (18.7) |
| Past use | 291 (30.8) | 1656(31.1) |
| Alcohol usea | ||
| Not at risk drinking | 816 (80.5) | 4710 (84.9) |
| At risk drinking | 198 (19.5) | 840 (15.1) |
| CD4 count, cells/mm3, median (IQR) | 334 (167, 488) | 426 (258, 616) |
Abbreviations: HIV, human immunodeficiency virus; IQR, interquartile range; PHQ-9, Patient Health Questionnaire-9.
aDefined as alcohol use disorders identification test score >4 for males and >3 for females.